{"id":3452,"date":"2026-04-02T16:20:15","date_gmt":"2026-04-02T16:20:15","guid":{"rendered":"https:\/\/www.cansativa.de\/?p=3452"},"modified":"2026-04-08T05:47:33","modified_gmt":"2026-04-08T05:47:33","slug":"medicinal-cannabis-and-evidence-what-the-data-actually-show-today","status":"publish","type":"post","link":"https:\/\/www.cansativa.de\/en\/2026\/04\/02\/medicinal-cannabis-and-evidence-what-the-data-actually-show-today\/","title":{"rendered":"Medicinal Cannabis and Evidence \u2013 What the Data Actually Show Today"},"content":{"rendered":"

[vc_row row_height_percent=”0″ override_padding=”yes” h_padding=”3″ top_padding=”3″ bottom_padding=”3″ overlay_alpha=”50″ gutter_size=”6″ column_width_percent=”100″ shift_y=”0″ z_index=”0″ uncode_shortcode_id=”166943″][vc_column width=”2\/3″][vc_column_text uncode_shortcode_id=”158131″]<\/p>\n

Evidence also\u00a0emerges\u00a0beyond classical study designs<\/span><\/b>\u00a0<\/span><\/p>\n

A broad evidence\u00a0base for medicinal cannabis now exists worldwide, including documented treatment pathways and extensive real-world data from cohorts involving several tens of thousands of patients. These are complemented by clinical studies, even though randomized controlled trials are particularly difficult to conduct for cannabis flowers, for example because blinding is inherently limited in inhaled applications.<\/span>\u00a0<\/span><\/p>\n

A systematic overview of\u00a0international\u00a0literature also shows that the evidence base is continuously expanding and spans a wide range of indications (see the\u00a0<\/span>COPEIA database<\/span><\/a>\u00a0for healthcare\u00a0professionals). This is not an unusual situation. In many established therapeutic areas, care is based on a combination of studies, real-world care\u00a0data\u00a0and physicians\u2019 clinical experience. Gaps in the evidence therefore do not imply a lack of\u00a0efficacy but\u00a0often reflect structural limitations of research.<\/span>\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

Real-world care data show clear therapeutic patterns<\/span><\/b>\u00a0<\/span><\/p>\n

When medicinal cannabis was introduced in 2017,\u00a0the\u00a0BfArM\u00a0(Federal Institute for Drugs and Medical Devices)\u00a0established\u00a0a\u00a0<\/span>systematic accompanying survey<\/span><\/a>\u00a0in order to\u00a0evaluate care in a scientific manner.\u00a0The aim was to assess, on the basis of real prescribing data, how effective and meaningful its use is in practice, while at the same time creating a foundation for further research.<\/span>\u00a0<\/span><\/p>\n

The evaluation included data from around 21,000 treatments, allowing robust conclusions to be drawn about real-world care. One point is crucial, however: the accompanying survey only captures patients whose treatment was reimbursed by statutory health insurance. It therefore primarily reflects severe conditions for which reimbursement is possible. Areas of use involving less severe conditions, where medicinal cannabis is also used but often without reimbursement, are not included in these data.<\/span>\u00a0<\/span><\/p>\n

The evaluation also showed the indications in which medicinal cannabis is\u00a0most commonly used: chronic pain, at 76.4 percent, was by far the most frequent reason for prescription. Around 70 percent of patients reported an improvement in quality of life, and symptom relief was documented in approximately 75 percent of cases. The accompanying survey therefore clearly shows that medicinal cannabis delivers relevant therapeutic effects in clinical practice.<\/span>\u00a0<\/span><\/p>\n

These findings have also informed the further development of the regulatory framework, for example through\u00a0<\/span>removing\u00a0prior-approval requirements<\/span><\/a>\u00a0for certain specialist groups by the G-BA (Federal Joint Committee).<\/span>\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

Dosage form is part of the treatment decision<\/span><\/b>\u00a0<\/span><\/p>\n

Questions about evidence are often directed specifically at cannabis flowers. Yet it was precisely cannabis flowers that were made reimbursable through the 2017 reform. Inhaled and oral applications differ\u00a0substantially in\u00a0their pharmacokinetics, particularly\u00a0with regard to\u00a0onset of action, peak\u00a0effect\u00a0and duration of action. For many patients, inhaled use is therefore medically\u00a0appropriate\u00a0and indispensable. The assumption that inhaled therapies could\u00a0generally be\u00a0replaced by oral preparations falls short and does not reflect clinical reality.<\/span>\u00a0<\/span><\/p>\n

Prof. Dr. Kirsten R. M\u00fcller-Vahl also points this out, emphasizing that \u201c<\/span>the accompanying survey commissioned by the federal government clearly shows that cannabis flowers are overall more effective and improve quality of life more markedly than alternative finished medicinal products \u2013 with fewer adverse effects. The evidence base for oral cannabis extracts (with the exception of\u00a0the finished medicinal product Sativex\u00ae) is comparable to that for cannabis flowers<\/span><\/i>\u201d (<\/span>Medical Tribune<\/span><\/a>, 23 March 2026).<\/span>\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

Research takes time and requires reliable framework conditions<\/span><\/b>\u00a0<\/span><\/p>\n

Medicinal cannabis has only been a regular part of reimbursable care in Germany for a few years. For a therapeutic field of this scale, the evidence base is therefore still developing dynamically.\u00a0In addition, the regulatory environment continues to evolve. Large, long-term studies require planning certainty and considerable investment. The pace at which evidence is generated is therefore not only a scientific issue, but also a structural one.<\/span>\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

An evidence-based therapy still developing<\/span><\/b>\u00a0<\/span><\/p>\n

The evidence on medicinal cannabis is now broad and consistent enough to define clear areas of use and to support responsible prescribing. It includes clinical studies, extensive real-world care\u00a0data\u00a0and international experience.\u00a0Further research will continue to refine this picture.\u00a0One thing is clear: medicinal cannabis is not a therapy in an experimental stage, but an established part of medical care.\u00a0Against this backdrop, the regulatory framework should also be shaped consistently on the basis of evidence and should reflect actual clinical practice.<\/span>\u00a0<\/span><\/p>\n

 <\/p>\n

Anything else?<\/strong><\/p>\n

Do you have specific questions or suggestions for the Cannabis Briefing? Then send us an email to\u00a0briefing@www.cansativa.de<\/a>. If you are interested in revolutionising the cannabis industry with us, then stay tuned and follow our briefings!<\/p>\n

We wish you a good read!<\/p>\n

Best wishes from both of us,<\/span>[\/vc_column_text][vc_row_inner limit_content=””][vc_column_inner width=”1\/2″][vc_single_image media=”742″ media_width_use_pixel=”yes” uncode_shortcode_id=”192986″ media_width_pixel=”100″][vc_custom_heading heading_semantic=”h3″ text_size=”h3″ uncode_shortcode_id=”933932″ subheading=”Founder & Managing Director Cansativa”]Jakob Sons[\/vc_custom_heading][\/vc_column_inner][vc_column_inner width=”1\/2″][vc_single_image media=”741″ media_width_use_pixel=”yes” uncode_shortcode_id=”178400″ media_width_pixel=”100″][vc_custom_heading heading_semantic=”h3″ text_size=”h3″ uncode_shortcode_id=”607403″ subheading=”Founder & Managing Director Cansativa”]Benedikt Sons[\/vc_custom_heading][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column column_width_percent=”100″ gutter_size=”3″ back_color=”color-xsdn” overlay_alpha=”50″ radius=”std” shadow=”std” shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ sticky=”yes” width=”1\/3″ uncode_shortcode_id=”109911″ back_color_type=”uncode-palette”][vc_row_inner limit_content=””][vc_column_inner width=”1\/2″][vc_single_image media=”744″ media_width_percent=”100″ uncode_shortcode_id=”159176″][\/vc_column_inner][vc_column_inner column_width_percent=”100″ position_vertical=”middle” gutter_size=”3″ overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ width=”1\/2″ uncode_shortcode_id=”680020″][vc_single_image media=”742″ media_width_use_pixel=”yes” uncode_shortcode_id=”192986″ media_width_pixel=”100″][\/vc_column_inner][\/vc_row_inner][vc_custom_heading heading_semantic=”h3″ text_size=”h3″ uncode_shortcode_id=”850716″ subheading=”Founder & Managing Director Cansativa”]Jakob Sons[\/vc_custom_heading][vc_separator sep_color=”,Default”][vc_row_inner limit_content=””][vc_column_inner width=”1\/2″][vc_single_image media=”743″ media_width_percent=”100″ uncode_shortcode_id=”886589″][\/vc_column_inner][vc_column_inner column_width_percent=”100″ position_vertical=”middle” gutter_size=”3″ overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ width=”1\/2″ uncode_shortcode_id=”680020″][vc_single_image media=”741″ media_width_use_pixel=”yes” uncode_shortcode_id=”178400″ media_width_pixel=”100″][\/vc_column_inner][\/vc_row_inner][vc_custom_heading heading_semantic=”h3″ text_size=”h3″ uncode_shortcode_id=”132885″ subheading=”Founder & Managing Director Cansativa”]Benedikt Sons[\/vc_custom_heading][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Medicinal cannabis has been part of routine medical care in Germany since 2017. The available evidence from real-world care data and international research clearly shows in which indications it offers therapeutic benefit. Medicinal cannabis is therefore an established treatment option with a well-defined benefit profile. <\/p>\n","protected":false},"author":5,"featured_media":1736,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[352],"tags":[],"class_list":["post-3452","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-briefing-en"],"yoast_head":"\nMedicinal Cannabis and Evidence \u2013 What the Data Actually Show Today - Cansativa Group<\/title>\n<meta name=\"description\" content=\"Cansativas Cannabis Briefing shows how real-world data, the BfArM survey and research support the therapeutic benefit of medicinal cannabis.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cansativa.de\/en\/2026\/04\/02\/medicinal-cannabis-and-evidence-what-the-data-actually-show-today\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Medicinal Cannabis and Evidence \u2013 What the Data Actually Show Today - 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