{"id":2328,"date":"2025-05-09T07:51:40","date_gmt":"2025-05-09T07:51:40","guid":{"rendered":"https:\/\/www.cansativa.de\/?p=2328"},"modified":"2025-05-09T07:51:40","modified_gmt":"2025-05-09T07:51:40","slug":"evidence-based-care-latest-medical-cannabis-studie","status":"publish","type":"post","link":"https:\/\/www.cansativa.de\/en\/2025\/05\/09\/evidence-based-care-latest-medical-cannabis-studie\/","title":{"rendered":"Medical Cannabis in the Spotlight: Evidence &#038; Emerging Research"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;3&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;6&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;166943&#8243;][vc_column width=&#8221;2\/3&#8243;][vc_column_text uncode_shortcode_id=&#8221;262874&#8243;]<b><span data-contrast=\"auto\">New Bioactive Compounds from Natural Product Chemistry<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">An example of cutting-edge basic research comes from Jung et al. (Pharmaceuticals 2025;18(4):521). The authors were the first to isolate two previously unknown cannabinoids \u2013 including cannabielsoxa \u2013 as well as chlorin-type metabolites from the flowers of Cannabis sativa. While classic cannabinoids demonstrated strong antitumor effects against neuroblastoma cells in cell culture, the chlorin derivatives open up an entirely new therapeutic avenue: their light-activated properties could be used in photodynamic treatments to selectively destroy tumor cells. For cancer patients whose standard therapies have reached their limits, these newly discovered compounds may become a valuable addition in the future.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">Long-Term Real-World Data from Australia<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The QUEST initiative provides impressive real-world evidence. In a prospective cohort of 2,353 patients treated with medical cannabis oil, quality of life and symptoms such as pain and fatigue improved within a few weeks and remained stable over twelve months. Remarkably, 70% of participants who had previously relied on opioids were able to reduce or completely discontinue their opioid dosage. Such practice-oriented observations are essential for demonstrating that medical cannabis should not be reserved as a last resort but integrated as a core part of modern pain therapy.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">Cannabis for Chemotherapy-Induced Nausea<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Grimison et al. investigated in a large Phase II\/III study whether THC:CBD capsules could relieve nausea and vomiting in patients experiencing severe symptoms despite standard antiemetic prophylaxis. Participants took 2.5\u202fmg THC plus 2.5\u202fmg CBD or placebo three times daily. The result: With the cannabis extract, the rate of complete response (no vomiting, no rescue medications) rose from 8% to 24% \u2013 a statistically significant increase of 16% (95% CI 4\u201328; p\u202f=\u202f0.01). Episodes of significant nausea, daily vomiting occurrences, and quality-of-life scores also improved. Side effects were mostly mild (sedation, dizziness, transient anxiety), with no serious adverse events. Even moderate doses thus proved to be an effective complement to antiemetic therapy.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">Conclusion &amp; Outlook<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The studies presented here are just a snapshot, but they expand our understanding of new therapeutic opportunities \u2013 from innovative antitumor approaches to alleviating treatment-related side effects. They also highlight where research priorities should lie: closing the gap between clinical trials and real-world practice so that medical cannabis gains further precision and trustworthiness, and finds more frequent integration into everyday prescribing.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span>[\/vc_column_text][vc_column_text uncode_shortcode_id=&#8221;150887&#8243;]<strong>Anything else?<\/strong><\/p>\n<p>Do you have specific questions or suggestions for the Cannabis Briefing? Then send us an email to\u00a0<a href=\"mailto:briefing@www.cansativa.de\">briefing@www.cansativa.de<\/a>. If you are interested in revolutionising the cannabis industry with us, then stay tuned and follow our briefings!<\/p>\n<p>We wish you a good read!<\/p>\n<p><span data-teams=\"true\">Best wishes from both of us,<\/span>[\/vc_column_text][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image media=&#8221;742&#8243; media_width_use_pixel=&#8221;yes&#8221; uncode_shortcode_id=&#8221;192986&#8243; media_width_pixel=&#8221;100&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;h3&#8243; uncode_shortcode_id=&#8221;933932&#8243; subheading=&#8221;Founder &amp; Managing Director Cansativa&#8221;]Jakob Sons[\/vc_custom_heading][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image media=&#8221;741&#8243; media_width_use_pixel=&#8221;yes&#8221; uncode_shortcode_id=&#8221;178400&#8243; media_width_pixel=&#8221;100&#8243;][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;h3&#8243; uncode_shortcode_id=&#8221;607403&#8243; subheading=&#8221;Founder &amp; Managing Director Cansativa&#8221;]Benedikt Sons[\/vc_custom_heading][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; back_color=&#8221;color-xsdn&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; sticky=&#8221;yes&#8221; radius=&#8221;std&#8221; shadow=&#8221;std&#8221; width=&#8221;1\/3&#8243; uncode_shortcode_id=&#8221;109911&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image media=&#8221;744&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;159176&#8243;][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;680020&#8243;][vc_single_image media=&#8221;742&#8243; media_width_use_pixel=&#8221;yes&#8221; uncode_shortcode_id=&#8221;192986&#8243; media_width_pixel=&#8221;100&#8243;][\/vc_column_inner][\/vc_row_inner][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;h3&#8243; uncode_shortcode_id=&#8221;850716&#8243; subheading=&#8221;Founder &amp; Managing Director Cansativa&#8221;]Jakob Sons[\/vc_custom_heading][vc_separator sep_color=&#8221;,Default&#8221;][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image media=&#8221;743&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;886589&#8243;][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;680020&#8243;][vc_single_image media=&#8221;741&#8243; media_width_use_pixel=&#8221;yes&#8221; uncode_shortcode_id=&#8221;178400&#8243; media_width_pixel=&#8221;100&#8243;][\/vc_column_inner][\/vc_row_inner][vc_custom_heading heading_semantic=&#8221;h3&#8243; text_size=&#8221;h3&#8243; uncode_shortcode_id=&#8221;132885&#8243; subheading=&#8221;Founder &amp; Managing Director Cansativa&#8221;]Benedikt Sons[\/vc_custom_heading][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Medical cannabis is already an evidence-based therapy firmly established for conditions such as chronic pain and spasticity. Of course, additional data are always needed to refine indications and tailor treatments more precisely to individual patient needs. In this issue of The Cannabis Briefing, we highlight recent studies that offer exciting insights. <\/p>\n","protected":false},"author":10,"featured_media":1736,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[352],"tags":[],"class_list":["post-2328","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-briefing-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Medical Cannabis in the Spotlight: Evidence &amp; Emerging Research - Cansativa Group<\/title>\n<meta name=\"description\" content=\"Discover the newest medical cannabis research\u2014from antitumor approaches to pain management and antiemesis in oncology.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cansativa.de\/en\/2025\/05\/09\/evidence-based-care-latest-medical-cannabis-studie\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Medical Cannabis in the Spotlight: Evidence &amp; 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